September 2010
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Higher blood sugar levels linked to lower brain function in diabetics, study shows

Results of a recent study by researchers at Wake Forest University Baptist Medical Center and colleagues show that the cognitive abilities as a means of operating Drop glucose in patients with type 2 diabetes. The study appears in the latest edition of Diabetes Care

Diabetes memory (mind) study, a sub-study on the control measures in cardiovascular diseases, diabetes risk test (Agreement), a statistically significant inverse relationship between A1C levels ( average blood glucose over a period of two to three months) and the themes of values on four cognitive tests. No club, but it was found between the rates of daily blood glucose (measured by plasma glucose fasting test) and test results.

For the study, researchers in 52 sites of 77 granted in the USA and Canada, one of 30 minutes a series of cognitive tests to nearly 3,000 people aged 55 and older.

“The tests are to study various aspects of memory function,” said Jeff Williamson, MD, MHS, Principal Investigator for the study by Wake Forest in the Clinic of the page. “For example, we have a situation in the east, the other between memory tasks or “multi-task, an important skill for people in need for their diabetes.”

The results showed that 1% A1C is a little lower in tests of psychomotor speed, global cognitive function, memory and manage multiple tasks.

“One little-known complications of type 2 diabetes is the memory decline leads to dementia, including Alzheimer’s dementia,” said Williamson, a professor of medicine, director of gerontology and geriatrics and director of research of Roen Kulynych Center for Memory and Cognition Research at the Wake Forest Baptist. “This study contributes to increasing evidence that the poorest blood glucose is closely related to the poorest of the memory function, and that these associations can be detected before a person of serious memory loss. ”

Diabetes is a risk factor for mild cognitive decline, vascular dementia and Alzheimer’s disease. Previous studies have shown that people with diabetes are 1.5 times more likely to make cognitive and dementia than those without diabetes. The ACCORD-MIND study supports the idea that the brain exposure to chronic increase of blood sugar can be part of the statement of this phenomenon.

Otherwise, the achievement of higher cognitive abilities have A1Cs because less with drugs and in control of their diabetes. The ACCORD-MIND study under the supervision by Williamson and a team from Wake Forest Baptist researchers to see, assuming a reduction in A1C could lead to an improvement of cognitive function.

Meanwhile, “people with type 2 diabetes and its providers must ensure, in situations where education and education on diabetes care, that patients should be a little more time for recording and information processing, “said Williamson. “Patients should also be open, with a family member on a regular basis and are confident that the continuation of management by monitoring their diabetes, nutrition, exercise and medication.”

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